Article
The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis.
Biomolecules - 21 Sept 2021
Rico-Díaz Agustín, Barreiro-Alonso Aída, Rey-Souto Cora, Becerra Manuel, Lamas-Maceiras Mónica, Cerdán M Esperanza, Vizoso-Vázquez Ángel
Abstract excerpt
In the traditional fermentative model yeast Saccharomyces cerevisiae, ScIxr1 is an HMGB (High Mobility Group box B) protein that has been considered as an important regulator of gene transcription in response to external changes like oxygen, carbon source, or nutrient availability. Kluyveromyces lactis is also a useful eukaryotic model, more similar to many human cells due to its respiratory metabolism. We cloned...
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