Article
Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: cross-talk between different adhesin gene clusters.
Molecular microbiology - 1 Feb 1994
Morschhäuser J, Vetter V, Emödy L, Hacker J
Abstract excerpt
The uropathogenic Escherichia coli strain 536 possesses two large, unstable DNA regions on its chromosome, which were termed pathogenicity islands (pais). Deletions of pais, which occur with relatively high frequency in vitro and in vivo, lead to avirulent mutants. The genetic determinants for pr...
Topics
- Amino Acid Sequence
- Bacterial Adhesion
- Base Sequence
- Chromosomes, Bacterial
- DNA Primers
- DNA, Bacterial
- Escherichia coli
- Fimbriae, Bacterial
- Genes, Regulator
- Genetic Complementation Test
- Molecular Sequence Data