Article
UropathogenicEscherichia coliExpress Type 1 Fimbriae Only in Surface Adherent Populations Under Physiological Growth Conditions
19 Aug 2015
Abstract excerpt
BACKGROUND: Most uropathogenic Escherichia coli (UPEC) strains harbor genes encoding adhesive type 1 fimbria (T1F). T1F is a key factor for successful establishment of urinary tract infection. However, UPEC strains typically do not express T1F in the bladder urine, and little is understood about its induction in vivo. METHODS: A flow chamber infection model was used to grow UPEC under conditions simulating...
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