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Article

Highly sensitive and specific bioassay for measuring bioactive TGF-β

20 Mar 2006

Abstract excerpt

BACKGROUND: Transforming Growth Factor-beta (TGF-beta) regulates key biological processes during development and in adult tissues and has been implicated in many diseases. To study the biological functions of TGF-beta, sensitive, specific, and convenient bioassays are necessary. Here we describe a new cell-based bioassay that fulfills these requirements. RESULTS: Embryonic fibroblasts from Tgfb1-/- mice were...

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PMID: 16549026
DOI: 10.1186/1471-2121-7-15

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