Article
Intimin from enteropathogenic Escherichia coli mediates remodelling of the eukaryotic cell surface.
Microbiology (Reading, England) - 1 Jun 2000
Phillips Alan D, Giròn Jorgé, Hicks Susan, Dougan Gordon, Frankel Gad
Abstract excerpt
Adhesion to cultured epithelial cells by enteropathogenic Escherichia coli (EPEC) is associated with extensive rearrangement of the host cell cytoskeleton. Evidence has been presented that EPEC adhesion is associated with activation of signal transduction pathways leading to production of a characteristic histopathological feature known as the attaching and effacing (A/E) lesion. A/E lesion formation requires...
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