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Article

A c-kit-negative gastrointestinal stromal tumor with a platelet-derived growth factor receptor alpha mutation.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Mar 2006

Isaac Jorge C, Willmore Carlynn, Holden Joseph A, Layfield Lester J

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are well-recognized mesenchymal neoplasms of the intestinal tract. A diagnosis of GIST is not always possible using IHC techniques for detection of c-kit. The authors describe a 64-year-old man who presented with an upper abdominal quadrant mass. Histology showed a predominantly epithelioid neoplasm with focal "spindle cell" areas. IHC studies were positive for muscle...

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Identifiers

PMID: 16540731
DOI: 10.1097/01.pai.0000156866.84350.ec

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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