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Article

A simplified flow cytometric assay identifies children with acute lymphoblastic leukemia who have a superior clinical outcome.

Blood - 1 Jul 2006

Coustan-Smith Elaine, Ribeiro Raul C, Stow Patricia, Zhou Yinmei, Pui Ching-Hon, Rivera Gaston K, Pedrosa Francisco, Campana Dario

Abstract excerpt

Bone marrow normal lymphoid progenitors (CD19+, CD10+, and/or CD34+) are exquisitely sensitive to corticosteroids and other antileukemic drugs. We hypothesized that, in patients with B-lineage acute lymphoblastic leukemia (ALL), cells with this phenotype detected early in treatment should be leukemic rather than normal. We therefore developed a simple and inexpensive flow cytometric assay for such cells and...

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Source

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Identifiers

PMID: 16537802
DOI: 10.1182/blood-2006-01-0066
PMCID: PMC1895825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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