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Article

A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia

25 Apr 2007

Abstract excerpt

To identify novel predictors of outcome in childhood acute lymphoblastic leukemia (ALL), we analyzed gene expression in the leukemic cells of 187 children with newly diagnosed ALL and compared the findings with minimal residual disease (MRD) results obtained on day 19 of remission induction treatment. Genes that showed a significant relationship to MRD were then tested for their capacity to predict leukemic...

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PMID: 17456722
DOI: 10.1182/blood-2007-01-068478

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