Article
Identification of a genetic cluster influencing memory performance and hippocampal activity in humans.
Proceedings of the National Academy of Sciences of the United States of America - 14 Mar 2006
de Quervain Dominique J-F, Papassotiropoulos Andreas
Abstract excerpt
Experimental work in animals has shown that memory formation depends on a cascade of molecular events. Here we show that variability of human memory performance is related to variability in genes encoding proteins of this signaling cascade, including the NMDA and metabotrobic glutamate receptors, adenylyl cyclase, CAMKII, PKA, and PKC. The individual profile of genetic variability in these signaling molecules...
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