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Article

Interactions between Ca2+-ATPase and the pentameric form of phospholamban in two-dimensional co-crystals.

Biophysical journal - 1 Jun 2006

Stokes David L, Pomfret Andrew J, Rice William J, Glaves John Paul, Young Howard S

Abstract excerpt

Phospholamban (PLB) physically interacts with Ca(2+)-ATPase and regulates contractility of the heart. We have studied this interaction using electron microscopy of large two-dimensional co-crystals of Ca(2+)-ATPase and the I40A mutant of PLB. Crystallization conditions were derived from those previously used for thin, helical crystals, but the addition of a 10-fold higher concentration of magnesium had a dramatic...

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Identifiers

PMID: 16533842
DOI: 10.1529/biophysj.105.079640
PMCID: PMC1459492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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