Article
A genome-wide screen for acrophobia susceptibility loci in a Finnish isolate.
Scientific reports - 20 Dec 2016
Misiewicz Zuzanna, Hiekkalinna Tero, Paunio Tiina, Varilo Teppo, Terwilliger Joseph D, Partonen Timo, Hovatta Iiris
Abstract excerpt
Acrophobia, an abnormal fear of heights, is a specific phobia characterized as apprehension cued by the occurrence or anticipation of elevated spaces. It is considered a complex trait with onset influenced by both genetic and environmental factors. Identification of genetic risk variants would provide novel insight into the genetic basis of the fear of heights phenotype and contribute to the molecular-level...
Topics
- Alleles
- Anticipation, Psychological
- Chromosome Mapping
- Female
- Finland
- Genetic Linkage
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Haplotypes
- Humans
- Male
- Microsatellite Repeats
- Pedigree
- Phobic Disorders
