Article
Linkage analysis of alternative anxiety phenotypes in multiply affected panic disorder families.
Psychiatric genetics - 1 Jun 2012
Fyer Abby J, Costa Ramiro, Haghighi Fatemeh, Logue Mark W, Knowles James A, Weissman Myrna M, Hodge Susan E, Hamilton Steven P
Abstract excerpt
BACKGROUND: The choice of phenotype definitions for genetic studies of panic and phobic disorders is complicated by family, twin, and neurobiological data indicating both distinct and shared risk factors as well as heterogeneity within categories. We have previously reported a genome scan in 120 multiplex panic disorder (PD) families using a phenotype that closely adhered to the Diagnostic and Statistical Manual...
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