Article

Fibroblasts as an in vitro model of circadian genetic and genomic studies: A temporal analysis

2023-05-22

Abstract excerpt

<h4>ABSTRACT</h4> Bipolar disorder (BD) is a heritable disorder characterized by shifts in mood that manifest in manic or depressive episodes. Clinical studies have identified abnormalities of the circadian system in BD patients as a hallmark of underlying pathophysiology. Fibroblasts are a well-established in vitro model for measuring circadian patterns. We set out to examine the underlying genetic architecture...

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Literature Corpus work: 33e01100-6b51-5842-925e-1ffd83860cab
DOI: 10.1101/2023.05.19.541494

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