Article

Fibroblasts as an in vitro model of circadian genetic and genomic studies

2024-05-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Bipolar disorder (BD) is a heritable disorder characterized by shifts in mood that manifest in manic or depressive episodes. Clinical studies have identified abnormalities of the circadian system in BD patients as a hallmark of underlying pathophysiology. Fibroblasts are a well-established in vitro model for measuring circadian patterns. We set out to examine the...

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Literature Corpus work: 3b07a768-85fb-5d28-b240-7afe83755660
DOI: 10.21203/rs.3.rs-4397132/v1

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