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BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on the Creighton University historical series of high risk families.

Familial cancer - 1 Jan 2006

Sinilnikova Olga M, Mazoyer Sylvie, Bonnardel Colette, Lynch Henry T, Narod Steven A, Lenoir Gilbert M

Abstract excerpt

Over the last four decades, Henry Lynch has collected pedigrees and samples from high risk breast and/or ovarian cancer families, generating a unique resource for the study of breast cancer susceptibility. These families have made a major contribution to increasing our knowledge in the cancer genetic susceptibility field, allowing the discovery of a genetic association between breast and ovarian cancer...

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Source

Identifiers

PMID: 16528604
DOI: 10.1007/s10689-005-2571-7

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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