Article
Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families.
British journal of cancer - 1 Apr 2000
Osorio A, Barroso A, Martínez B, Cebrián A, San Román J M, Lobo F, Robledo M, Benítez J
Abstract excerpt
It is estimated that about 5-10% of breast cancer cases may be due to inherited predisposition. Until now, two main susceptibility genes have been identified: BRCA1 and BRCA2. The first linkage and mutational studies suggested that mutations in these two genes would account for the majority of hi...
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