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Article

Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families.

British journal of cancer - 1 Apr 2000

Osorio A, Barroso A, Martínez B, Cebrián A, San Román J M, Lobo F, Robledo M, Benítez J

Abstract excerpt

It is estimated that about 5-10% of breast cancer cases may be due to inherited predisposition. Until now, two main susceptibility genes have been identified: BRCA1 and BRCA2. The first linkage and mutational studies suggested that mutations in these two genes would account for the majority of high-risk breast cancer families, but recent studies show how the proportion of families due to BRCA1 or BRCA2 mutations...

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Source

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Identifiers

PMID: 10755399
DOI: 10.1054/bjoc.1999.1089
PMCID: PMC2374482

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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