Article
BRCA1 and BRCA2 and breast cancer incidence: a review.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 1999
Bishop D T
Abstract excerpt
BACKGROUND: Epidemiological studies have repeatedly shown that having a family history is a risk factor for female (and male) breast cancer. Some rare families have many (4 or more) cases of early onset breast cancer (some of which also include women with ovarian cancer) which are most clearly explained by an autosomal dominant gene with high penetrance. DESIGN: Families with multiple cases of early onset breast...
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