Article
[Thermal denaturation of eukaryotic class 1 translation termination factor eRF1. Relationship between stability of the eRF1 molecule and alteration of functional activity of its mutants].
Molekuliarnaia biologiia - 1 Jan 2000
Mit'kevich V A, Kononenko A V, Oparina N Iu, Kolosov P M, Makarov A A, Kiselev L L
Abstract excerpt
Thermal denaturation of eukaryotic class-1 translation termination factor eRF1 and its mutants was examined using differential scanning microcalorimetry (DSK). Changes of free energy caused by mutants in the N domain of human eRF1 were calculated. Melting of eRF1 molecule composed of three indivi...
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