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Article

Genotypic heterogeneity and correlation to intergenic haplotype within high HbF beta-thalassemia intermedia.

European journal of haematology - 1 Apr 2006

Papachatzopoulou Adamantia, Kourakli Alexandra, Makropoulou Panagiota, Kakagianne Theodora, Sgourou Argyro, Papadakis Manousos, Athanassiadou Aglaia

Abstract excerpt

OBJECTIVES: A molecular study was carried out of beta-thalassemia intermedia patients, compound heterozygotes for mutations usually found in beta-thalassemia major, with high levels of HbF in the absence of hereditary persistence of fetal hemoglobin (HPFH) syndrome. Our objective was to locate cis-DNA structures, DNA haplotypes, motifs, or polymorphisms that may correlate with the presence of high HbF. METHODS:...

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Source

Identifiers

PMID: 16519704
DOI: 10.1111/j.1600-0609.2005.00618.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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