Article
Two beta-globin cluster-linked polymorphic loci in thalassemia patients of variable levels of fetal hemoglobin.
European journal of haematology - 1 Jul 2005
Bandyopadhyay Sanmay, Mondal Bama Charan, Sarkar Pabak, Chandra Sarmila, Das M K, Dasgupta Uma B
Abstract excerpt
OBJECTIVE: To correlate different polymorphisms of the beta-globin cluster with fetal hemoglobin (HbF) level in beta-thalassemia and E-beta thalassemia patients. METHODS: Fifteen thalassemia patients, seven with high HbF and not requiring transfusion, eight with lower HbF and requiring transfusion were studied for beta-globin mutation, concurrent inheritance of alpha-thalassemia, RFLP haplotype, a C-->T...
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