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Article

Genome-wide identification of novel genomic islands that contribute to<i>Salmonella</i>virulence in mouse systemic infection

10 Jun 2009

Abstract excerpt

Salmonella pathogenicity islands are inserted into the genome by horizontal gene transfer and are required for expression of full virulence. Here, we performed tRNA scanning of the genome of Salmonella enterica serovar Typhimurium and compared it with that of nonpathogenic Escherichia coli in order to identify genomic islands that contribute to Salmonella virulence. Using deletion analysis, we identified four...

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PMID: 19583791
DOI: 10.1111/j.1574-6968.2009.01686.x

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