Article
Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature-tagged transposon mutagenesis.
Molecular microbiology - 1 Apr 1999
Darwin A J, Miller V L
Abstract excerpt
Pathogenic Yersinia species are associated with both localized and systemic infections in mammalian hosts. In this study, signature-tagged transposon mutagenesis was used to identify Yersinia enterocolitica genes required for survival in a mouse model of infection. Approximately 2000 transposon insertion mutants were screened for attenuation. This led to the identification of 55 mutants defective for survival in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
