Article
Evidence that variation in the peripheral benzodiazepine receptor (PBR) gene influences susceptibility to panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2006
Nakamura Kazuhiko, Yamada Kazuo, Iwayama Yoshimi, Toyota Tomoko, Furukawa Aizou, Takimoto Takahiro, Terayama Hayato, Iwahashi Kazuhiko, Takei Nori, Minabe Yoshio, Sekine Yoshimoto, Suzuki Katsuaki, Iwata Yasuhide, Pillai Anitha, Nakamoto Yurie, Ikeda Kazutaka, Yoshii Mitsunobu, Fukunishi Isao, Yoshikawa Takeo, Mori Norio
Abstract excerpt
Panic disorder (PD) is the repeated sudden occurrence of panic attacks, episodes characterized by psychological symptoms. Peripheral benzodiazepine receptor (PBR) is closely associated with personality traits for anxiety tolerance, and that it holds promise as a biological marker of stressful conditions. We have performed association analyses using the polymorphism to determine the PBR in PD. We screened the...
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