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Article

Neurovirulent strains of herpes simplex virus type 1 are not necessarily competent for reactivatable latency.

Acta medica Okayama - 1 Apr 1991

Arao Y, Hatano A, Yamada M, Uno F, Nii S

Abstract excerpt

Ability of two neurovirulent strains (F and +GC (LPV) Miyama) of herpes simplex virus type 1 (HSV-1) to establish and maintain reactivatable latency in trigeminal ganglia (TG) was compared after intranasal inoculation of mice. The +GC (LPV) Miyama strain showed a very low rate of virus reactivation in explant cultures of TG, while the F strain showed a high rate of reactivation. These data indicate that...

Topics

Administration, Intranasal
Animals
Mice
Mutation
Simplexvirus
Trigeminal Ganglion
Virulence
Virus Activation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1651044
DOI: 10.18926/AMO/32190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1651044-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Neurovirulent strains of herpes simplex virus type 1 are not necessarily competent for reactivatable latency.PMID 1651044Read ↗

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