Article
Role for gamma interferon in control of herpes simplex virus type 1 reactivation.
Journal of virology - 1 Apr 1999
Cantin E, Tanamachi B, Openshaw H
Abstract excerpt
Observation of chronic inflammatory cells and associated high-level gamma interferon (IFN-gamma) production in ganglia during herpes simplex type 1 (HSV-1) latent infection in mice (E. M. Cantin, D. R. Hinton, J. Chen, and H. Openshaw, J. Virol. 69:4898-4905, 1995) prompted studies to determine a role of IFN-gamma in maintaining latency. Mice lacking IFN-gamma (GKO mice) or the IFN-gamma receptor (RGKO mice) were...
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