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Article

Human androgen deficiency: insights gained from androgen receptor knockout mouse models

1 Jan 2014

Abstract excerpt

The mechanism of androgen action is complex. Recently, significant advances have been made into our understanding of how androgens act via the androgen receptor (AR) through the use of genetically modified mouse models. A number of global and tissue-specific AR knockout (ARKO) models have been generated using the Cre-loxP system which allows tissue- and/or cell-specific deletion. These ARKO models have examined a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24480924
DOI: 10.4103/1008-682x.122590

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