Article
Potential dual molecular interaction of the Drosophila 7-pass transmembrane cadherin Flamingo in dendritic morphogenesis.
Journal of cell science - 15 Mar 2006
Kimura Hiroshi, Usui Tadao, Tsubouchi Asako, Uemura Tadashi
Abstract excerpt
Seven-pass transmembrane cadherins (7-TM cadherins) play pleiotropic roles in epithelial planar cell polarity, shaping dendritic arbors and in axonal outgrowth. In contrast to their role in planar polarity, how 7-TM cadherins control dendritic and axonal outgrowth at the molecular level is largely unknown. Therefore, we performed extensive structure-function analysis of the Drosophila 7-TM cadherin Flamingo (Fmi)...
Topics
- Animals
- Cadherins
- Cell Polarity
- Dendrites
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Models, Chemical
- Morphogenesis
- Mutation
- Neurons
- Structure-Activity Relationship
