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Article

Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility.

Journal of biomedical science - 1 May 2006

Yu Jyh-Cherng, Hsu Huan-Ming, Chen Shou-Tung, Hsu Giu-Cheng, Huang Chiun-Sheng, Hou Ming-Feng, Fu Yi-Ping, Cheng Ting-Chih, Wu Pei-Ei, Shen Chen-Yang

Abstract excerpt

The reproductive hormone, estrogen, contributes to the development of breast cancer by binding to the estrogen receptor (ER) in the nucleus, triggering cell growth and tumor promotion. In addition to its role in regulating target genes and signaling pathways involved in cell cycle progression, the ER-signaling pathway may regulate the expression of chromatin-remodeling gene, Metastasis-associated 3 (MTA3), or...

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Source

Identifiers

PMID: 16502042
DOI: 10.1007/s11373-006-9069-7

Genes

MTA3
MTA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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