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Article

Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis.

Oncogene - 13 Jul 2006

Ma W, Xia X, Stafford L J, Yu C, Wang F, LeSage G, Liu M

Abstract excerpt

Transcription factors with helix-loop-helix (HLH) motif play critical roles in controlling the expression of genes involved in lineage commitment, cell fate determination, proliferation, and tumorigenesis. To examine whether the newly identified HLH protein GCIP/CCNDBP1 modulates cell fate determination and plays a role in hepatocyte growth, proliferation, and hepatocarcinogenesis, we generated transgenic mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16501603
DOI: 10.1038/sj.onc.1209450

Genes

CCNDBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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