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Article

Identification of a cis-acting element responsible for negative regulation of the human UDP-glucose dehydrogenase gene expression.

Bioscience, biotechnology, and biochemistry - 1 Feb 2006

Vatsyayan Jaya, Lin Ching-Ting, Peng Hwei-Ling, Chang Hwan-You

Abstract excerpt

The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis of complex carbohydrates such as hyaluronan in many cell types, and is required for detoxification of toxic compounds in the liver. We previously defined the 714 bp 5'-flanking region of the UGDH gene as the core promoter, with putative negative regulatory elements...

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PMID: 16495656
DOI: 10.1271/bbb.70.401

Genes

UGDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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