Article
Identification of transcriptional targets associated with the expression of p210 Bcr-Abl.
European journal of haematology - 1 May 2006
Hickey Fionnuala B, Cotter Thomas G
Abstract excerpt
OBJECTIVES: Chronic myeloid leukaemia is caused by the expression of the p210 Bcr-Abl fusion protein which results from the Philadelphia translocation, t(9;22). This oncogene has been the focus of extensive research. However, the molecular mechanisms responsible for the haematological malignancy are not fully understood. The main objective of the current study was to identify novel transcriptional targets of...
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