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Article

Impact of interferon-gamma and interleukin-4 gene polymorphisms on development and progression of IgA nephropathy in Japanese patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Feb 2003

Masutani Kohsuke, Miyake Katsuhisa, Nakashima Hitoshi, Hirano Tadashi, Kubo Michiaki, Hirakawa Makoto, Tsuruya Kazuhiko, Fukuda Kyoichi, Kanai Hidetoshi, Otsuka Takeshi, Hirakata Hideki, Iida Mitsuo

Abstract excerpt

BACKGROUND: Cytokines have an important role in the pathogenesis and disease progression of immunoglobulin A (IgA) nephropathy. The aim of this study is to investigate the impact of gene polymorphisms of T helper cell subtype 1 (T(H)1)/T(H)2 cytokines, interferon-gamma (IFN-gamma), and interleukin-4 (IL-4) on IgA nephropathy in Japanese patients. METHODS: We investigated IFN-gamma gene (IFNG) and IL-4 gene (IL4)...

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Identifiers

PMID: 12552499
DOI: 10.1053/ajkd.2003.50046

Genes

IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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