Article
Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene.
Journal of the American Society of Nephrology : JASN - 1 Jul 2004
Li You-Ji, Du Yong, Li Cai-Xia, Guo Hui, Leung Joseph C K, Lam Man F, Yang Niansheng, Huang Fengxian, Chen Yun, Fang Ji-Qian, Maxwell Patrick H, Lai Kar N, Wang Yiming
Abstract excerpt
Immunoglobulin A nephropathy (IgAN) is considered to be a multifactorial disease with genetic and environmental factors contributing to its pathogenesis. The genes involved in susceptibility and progression of the disease have not yet been clearly elucidated. Megsin (SERPINB7) is an important can...
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