Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-6 g.-174G>C promoter polymorphism is associated with obesity in the EPIC-Potsdam Study.

Obesity (Silver Spring, Md.) - 1 Jan 2006

Klipstein-Grobusch Kerstin, Möhlig Matthias, Spranger Joachim, Hoffmann Kurt, Rodrigues Fabio U S, Sharma Arya M, Klaus Susanne, Pfeiffer Andreas F H, Boeing Heiner

Abstract excerpt

Homozygosity for the interleukin-6 (IL-6) g.-174G>C promoter polymorphism has recently been associated with indices of overweight. Homozygous subjects were observed to have reduced energy expenditure, suggesting that lower IL-6 gene transcription, caused by the IL-6 g.-174G>C promoter polymorphism, may be associated with obesity. The aim of this study was to investigate the association of this polymorphism with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Cross-Sectional Studies

Share to Interleukin-6

Share to Obesity

Share to Promoter Regions, Genetic

Share to Weight Gain

Source

Identifiers

PMID: 16493118
DOI: 10.1038/oby.2006.3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-6 g.-174G>C promoter polymorphism is associated with obesity in the EPIC-Potsdam Study.PMID 16493118Read ↗

A common polymorphism in the interleukin-6 gene promoter is associated with overweight.Semantic proximity Read ↗

Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes.Semantic proximity Read ↗

Impact of interleukin 6 -174G>C polymorphism on obesity-related metabolic disorders in people with excess in body weight.Semantic proximity Read ↗

Interleukin-6 -174 G/C promoter gene polymorphism and polycystic ovary syndrome: A cross sectional investigation in adult womenSemantic proximity Read ↗

Association between -174G>C polymorphism in the IL-6 promoter region and the risk of obesity: A meta-analysis.Semantic proximity Read ↗

Influence of interleukin-6 and G174C polymorphism in IL-6 gene on obesity and energy balance.Semantic proximity Read ↗

Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in women.Semantic proximity Read ↗

Body Composition and -174G/C Interleukin-6 Promoter Gene Polymorphism: Association with Progression of Insulin Resistance in Normal Weight Obese SyndromeSemantic proximity Read ↗

Effect of the interleukin-6 (-174) g/c promoter polymorphism on adiponectin and insulin sensitivity.Semantic proximity Read ↗

The interleukin 6 −174G/C Polymorphism is associated with indices of obesity in menSemantic proximity Read ↗

A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus.Semantic proximity Read ↗

C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.