Article
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.
Cancer research - 15 Feb 2006
Kim Il-Man, Ackerson Timothy, Ramakrishna Sneha, Tretiakova Maria, Wang I-Ching, Kalin Tanya V, Major Michael L, Gusarova Galina A, Yoder Helena M, Costa Robert H, Kalinichenko Vladimir V
Abstract excerpt
The proliferation-specific Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) regulates expression of cell cycle genes essential for progression into DNA replication and mitosis. Expression of Foxm1 is found in a variety of distinct human cancers including hepatocellular carcinomas, intrahepatic cholangiocarcinomas, basal cell carcinomas, ductal breast...
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