Article
WASP suppresses the growth defect of Saccharomyces cerevisiae las17Delta strain in the presence of WIP.
Biochemical and biophysical research communications - 7 Apr 2006
Rajmohan Rajamuthiah, Meng Lei, Yu Shangjuan, Thanabalu Thirumaran
Abstract excerpt
Wiskott-Aldrich syndrome is caused by alterations in the Wiskott-Aldrich syndrome protein (WASP) and several of these mutations affect WASP's interaction with WIP (WASP-interacting protein), suggesting that loss of interaction between WASP and WIP is causal to the disease. Las17p is the yeast homologue of WASP and las17Delta strain is unable to grow at 37 degrees C. We show that Human WASP suppresses the growth...
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