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Article

WASP suppresses the growth defect of Saccharomyces cerevisiae las17Delta strain in the presence of WIP.

Biochemical and biophysical research communications - 7 Apr 2006

Rajmohan Rajamuthiah, Meng Lei, Yu Shangjuan, Thanabalu Thirumaran

Abstract excerpt

Wiskott-Aldrich syndrome is caused by alterations in the Wiskott-Aldrich syndrome protein (WASP) and several of these mutations affect WASP's interaction with WIP (WASP-interacting protein), suggesting that loss of interaction between WASP and WIP is causal to the disease. Las17p is the yeast hom...

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Identifiers

PMID: 16488394
DOI: 10.1016/j.bbrc.2006.01.160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16488394-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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WASP suppresses the growth defect of Saccharomyces cerevisiae las17Delta strain in the presence of WIP.PMID 16488394Read ↗

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WIP, a protein associated with Wiskott–Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cellsSemantic proximity Read ↗

The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.Semantic proximity Read ↗

The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP)Semantic proximity Read ↗

Phosphorylation of the WH2 domain in yeast Las17/WASP regulates G-actin binding and protein function during endocytosis.Semantic proximity Read ↗

A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP.Semantic proximity Read ↗

WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)Semantic proximity Read ↗

Triple-color FRET analysis reveals conformational changes in the WIP-WASp actin-regulating complex.Semantic proximity Read ↗

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeletonSemantic proximity Read ↗

X-linked thrombocytopenia caused by a mutation in the Wiskott-Aldrich syndrome (WAS) gene that disrupts interaction with the WAS protein (WASP)-interacting protein (WIP)Semantic proximity Read ↗

Saccharomyces cerevisiae Bzz1p Is Implicated with Type I Myosins in Actin Patch Polarization and Is Able To Recruit Actin-Polymerizing Machinery In VitroSemantic proximity Read ↗

New Structural Insights into Formation of the Key Actin Regulating WIP-WASp Complex Determined by NMR and Molecular Imaging.Semantic proximity Read ↗

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