Article
Induction of gamma delta transposition in response to elevated glucose-6-phosphate levels.
Mutation research - 1 Jul 1991
Lee A T, Cerami A
Abstract excerpt
The nonenzymatic glycosylation of nucleic acids in vitro by the reducing sugars, glucose or glucose-6-phosphate, alters both physical and biological properties. Recent investigations have demonstrated that elevated intracellular levels of glucose-6-phosphate in glycolytic mutants of E. coli resulted in a concentration-associated increase in mutations of a target plasmid. The majority of the plasmid mutations were...
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