Article
A mutation which affects both the specificity of PtsG sugar transport and the regulation of ptsG expression by Mlc in Escherichia coli.
Microbiology (Reading, England) - 1 Oct 2000
Plumbridge Jacqueline
Abstract excerpt
Normally glucosamine (GlcN) is not a substrate for EIICB(Glc) of the glucose phosphotransferase system (PTS), encoded by ptsG, but it is transported by the mannose (Man) PTS, encoded by manXYZ. A mutation, umgC, has been described in Escherichia coli which allows a strain mutated in the Man PTS to grow on GlcN. The umgC mutation was mapped to the ptsG region and was proposed to make ptsG expression constitutive....
Topics
- Alleles
- Cloning, Molecular
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glucosamine
- Mutation
- Phosphoenolpyruvate Sugar Phosphotransferase System
- RNA, Bacterial
- RNA, Messenger
- Repressor Proteins