HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example.

doi:10.1016/j.autrev.2005.06.002

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HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example.

Autoimmunity reviews - 1 Mar 2006

Gorodezky Clara, Alaez Carmen, Murguía Andrea, Rodríguez Araceli, Balladares Sandra, Vazquez Miriam, Flores Hilario, Robles Carlos

Abstract excerpt

Autoimmune diseases need to be considered at a genetic and mechanistic level. T1D is an autoimmune, chronic, multifactorial and polygenic disease characterized by the destruction of the pancreatic beta-cells associated with long term dysfunction of several organs and tissues. Mechanisms of susceptibility include epi-genetic and post-transcriptional effects that regulate transmission and expression of the...

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HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example.

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