Article
Detecting overlapping coding sequences in virus genomes.
BMC bioinformatics - 16 Feb 2006
Firth Andrew E, Brown Chris M
Abstract excerpt
BACKGROUND: Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of overlapping coding and non-coding functional elements, which can result in unusual patterns of codon usage; conservation between related sequences can be difficult to interpret--especially within overlapping genes; and viruses often employ non-canonical...
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