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Article

Inactivation of the putative tetracycline resistance gene HP1165 in Helicobacter pylori led to loss of inducible tetracycline resistance.

Archives of microbiology - 1 May 2006

Li Yuhuan, Dannelly H Kathleen

Abstract excerpt

Tetracycline has been used with other antibiotics in treatment of Helicobacter pylori infection. However, tetracycline resistance has developed in H. pylori clinical isolates, rendering treatment failure. Mutations in 16S rRNA genes have been reported to mediate tetracycline resistance in some isolates. The diversity of tetracycline resistance cases suggests multiple genes are involved. HP1165, a putative...

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Share to Cloning, Molecular
Share to Helicobacter Infections
Share to Helicobacter pylori

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis, Insertional

Share to Protein Biosynthesis

Share to RNA, Ribosomal, 16S

Share to Tetracycline Resistance

Share to Transformation, Bacterial

Source

Identifiers

PMID: 16482431
DOI: 10.1007/s00203-006-0093-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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