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Article

A change in PBP1 is involved in amoxicillin resistance of clinical isolates of Helicobacter pylori.

The Journal of antimicrobial chemotherapy - 1 Dec 2002

Okamoto Takeshi, Yoshiyama Hironori, Nakazawa Teruko, Park In-Dal, Chang Myung-Woong, Yanai Hideo, Okita Kiwamu, Shirai Mutsunori

Abstract excerpt

Reports on the isolation of amoxicillin-resistant Helicobacter pylori are increasing worldwide, which may cause serious problems in eradication therapy. To elucidate the mechanism of amoxicillin resistance of H. pylori, penicillin-binding proteins (PBPs) of amoxicillin-resistant strains isolated in Korea were analysed. Three PBPs (66, 63 and 60 kDa) were identified in both amoxicillin-resistant and -susceptible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12461003
DOI: 10.1093/jac/dkf140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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