Article
Effects of 16S rRNA gene mutations on tetracycline resistance in Helicobacter pylori.
Antimicrobial agents and chemotherapy - 1 Sept 2003
Gerrits Monique M, Berning Marco, Van Vliet Arnoud H M, Kuipers Ernst J, Kusters Johannes G
Abstract excerpt
The triple-base-pair 16S rDNA mutation AGA(926-928)-->TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining...
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