Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Helicobacter pylori TolC efflux pump confers resistance to metronidazole.

Antimicrobial agents and chemotherapy - 1 Apr 2005

van Amsterdam Karin, Bart Aldert, van der Ende Arie

Abstract excerpt

In Helicobacter pylori, the contribution of efflux proteins to antibiotic resistance is not well established. As translocases that act in parallel may have overlapping substrate specificities, the loss of function of one such translocase may be compensated for by that of another translocase with no effect on susceptibilities to antibiotics. The genome of H. pylori 26695 was assessed for the presence of putative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Outer Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacterial Proteins

Share to Drug Resistance, Bacterial

Share to Helicobacter pylori

Share to Metronidazole

Share to Microbial Sensitivity Tests

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 15793129
DOI: 10.1128/AAC.49.4.1477-1482.2005
PMCID: PMC1068630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Helicobacter pylori TolC efflux pump confers resistance to metronidazole.PMID 15793129Read ↗

Association of hp1181 and hp1184 Genes With the Active Efflux Phenotype in Multidrug-Resistant Isolates of Helicobacter pyloriSemantic proximity Read ↗

Helicobacter pylori Efflux Pumps: A Double-Edged Sword in Antibiotic Resistance and Biofilm FormationSemantic proximity Read ↗

Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genesSemantic proximity Read ↗

Efflux pumps potential drug targets to circumvent drug Resistance – Multi drug efflux pumps of Helicobacter pyloriSemantic proximity Read ↗

Molecular Mechanisms of β-Lactam Resistance and Its Contribution to Multidrug Resistance in Helicobacter pylori.Semantic proximity Read ↗

16S rRNA mutation-mediated tetracycline resistance in Helicobacter pylori.Semantic proximity Read ↗

Transporters HP0939, HP0497, and HP0471 participate in intrinsic multidrug resistance and biofilm formation in Helicobacter pylori by enhancing drug effluxSemantic proximity Read ↗

Inactivation of the putative tetracycline resistance gene HP1165 in Helicobacter pylori led to loss of inducible tetracycline resistance.Semantic proximity Read ↗

High-level beta-lactam resistance associated with acquired multidrug resistance in Helicobacter pylori.Semantic proximity Read ↗

Mutations in the 16S rRNA genes of Helicobacter pylori mediate resistance to tetracycline.Semantic proximity Read ↗

Proton motive force-dependent efflux of tetracycline in clinical isolates of Helicobacter pylori.Semantic proximity Read ↗

Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.