Article
16S rRNA mutation-mediated tetracycline resistance in Helicobacter pylori.
Antimicrobial agents and chemotherapy - 1 Sept 2002
Gerrits Monique M, de Zoete Marcel R, Arents Niek L A, Kuipers Ernst J, Kusters Johannes G
Abstract excerpt
Most Helicobacter pylori strains are susceptible to tetracycline, an antibiotic commonly used for the eradication of H. pylori. However, an increase in incidence of tetracycline resistance in H. pylori has recently been reported. Here the mechanism of tetracycline resistance of the first Dutch tetracycline-resistant (Tet(r)) H. pylori isolate (strain 181) is investigated. Twelve genes were selected from the...
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