Article
Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development.
Development (Cambridge, England) - 1 Mar 2006
Eberhart Johann K, Swartz Mary E, Crump Justin Gage, Kimmel Charles B
Abstract excerpt
Hedgehog (Hh) signaling plays multiple roles in the development of the anterior craniofacial skeleton. We show that the earliest function of Hh is indirect, regulating development of the stomodeum, or oral ectoderm. A subset of post-migratory neural crest cells, that gives rise to the cartilages of the anterior neurocranium and the pterygoid process of the palatoquadrate in the upper jaw, condenses upon the upper...
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