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Article

The phenotype and survival of antigen-stimulated transgenic CD4 T cells in vivo: the influence of persisting antigen.

International immunology - 1 Apr 2006

Yang C-P, Sparshott S M, Duffy D, Garside P, Bell E B

Abstract excerpt

Naive and primed/memory CD4 T cells are distinguished by changes in the expression of activation/adhesion molecules that correspond with an altered function. Adoptively transferred TCR transgenic (tg) CD4 T cells specific for ovalbumin peptide (OVA-pep) were analysed for changing phenotype and the speed of change in vivo following antigen challenge with alum-precipitated (ap) OVA-pep, a conjugate that stimulated...

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PMID: 16481344
DOI: 10.1093/intimm/dxh392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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