Article
Altered gut transcriptome in spondyloarthropathy.
Annals of the rheumatic diseases - 1 Oct 2006
Laukens D, Peeters H, Cruyssen B V, Boonefaes T, Elewaut D, De Keyser F, Mielants H, Cuvelier C, Veys E M, Knecht K, Van Hummelen P, Remaut E, Steidler L, De Vos M, Rottiers P
Abstract excerpt
BACKGROUND: Intestinal inflammation is a common feature of spondyloarthropathy (SpA) and Crohn's disease. Inflammation is manifested clinically in Crohn's disease and subclinically in SpA. However, a fraction of patients with SpA develops overt Crohn's disease. AIMS: To investigate whether subclinical gut lesions in patients with SpA are associated with transcriptome changes comparable to those seen in Crohn's...
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