Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles

Abstract excerpt

INTRODUCTION: Axial spondyloarthropathy (SpA) is a group of inflammatory diseases, with ankylosing spondylitis as the prototype. SpA affects the axial skeleton, entheses, joints and, at times, the eyes. This study tested the hypothesis that SpA is characterized by a distinct pattern of gene expression in peripheral blood of affected individuals compared with healthy controls. METHODS: High-density, human GeneChip...

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