Article
TNF-alpha SNP haplotype frequencies in equidae.
Tissue antigens - 1 May 2006
Brown J J, Ollier W E R, Thomson W, Matthews J B, Carter S D, Binns M, Pinchbeck G, Clegg P D
Abstract excerpt
Tumour necrosis factor alpha (TNF-alpha) is a pro-inflammatory cytokine that plays a crucial role in the regulation of inflammatory and immune responses. In all vertebrate species the genes encoding TNF-alpha are located within the major histocompatability complex. In the horse TNF-alpha has been ascribed a role in a variety of important disease processes. Previously two single nucleotide polymorphisms (SNPs)...
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